Find emergency medical help if you experience any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your local doctor at once if you have any of these serious side effects after you buy Cefixime: diarrhea that is watery or bloody; fever, sore throat, and joint pain with a severe blistering, peeling, and red skin rash; numbness or tingly feeling; warmth, redness, or tingling under your skin; swelling in your hands or feet; fast or pounding heartbeats; chest pain, shortness of breath. Less serious side effects may include: mild nausea, stomach pain, constipation, loss of appetite; anxiety, drowsiness; increased night-time urination; headache; runny nose, sore throat, cough; or vaginal itching or discharge.