This medication should not be used with certain medical conditions. Consult your local doctor before you order Cenestin online if you have vaginal bleeding of unknown cause, certain cancers (e.g., breast cancer-especially non-metastatic type, cancer of the uterus or ovaries), current/history of blood clots, history of stroke or heart attack, liver disease. Before using this medication, tell your local physician doctor your medical history, especially of family medical history, asthma, diabetes, seizures, migraine headaches, heart disease, kidney disease, underactive thyroid, a certain hormone problem, mineral imbalance, mental/mood disorders, high blood pressure during pregnancy, yellowing eyes/skin during pregnancy or with past estrogen use, uterus problems, high blood cholesterol/fat levels, gallbladder disease, obesity, certain blood disorder, lupus.