Common side effects of generic Epivir drug might include headache, nausea, vomiting, diarrhea, insomnia, change in appetite, dizziness, weakness, muscle aches, skin rash, fever, chills, stuffy nose, cough, stomach pain, severe weakness, unusual fatigue, tingling of the hands or feet, rapid breathing, dark urine, yellowing of the eyes or skin, increased fat in the upper back and stomach areas, decreased fat in the arms and legs. The cause behind these effects and their long-term consequences are unknown. Talk about the potential role of exercise to decrease these adverse effects with a local doctor.