Generic Glibenclamide tablets side effects may include nausea, heartburn, stomach fullness, weight gain, persistent sore throat or fever, easy bleeding or bruising, stomach pain, yellowing eyes or skin, dark urine, unusual tiredness or weakness, unusual or sudden weight gain, mental/mood changes, swelling of the hands or feet, seizures. This medication can cause low blood sugar, with symptoms ranging from chills, cold sweat, blurred vision, dizziness, drowsiness, shaking, to rapid heart rate, weakness, headache, fainting, tingling of the hands or feet, or hunger. An allergic reaction to this drug is possible though not likely, and its symptoms might include rash, itching, swelling, dizziness, trouble breathing.