In clinical trials testing generic omeprazole, all of the side effects affecting 2% or more of participants were minor in nature and included headache, abdominal pain, nausea, diarrhea and flatulence. Other adverse reactions involving between one and two percent of trial participants included acid regurgitation, constipation, dizziness, rash, back pain and cough. All other side effects were exceedingly rare, so people observing more serious side effects after buying cheap omeprazole online should consult their local physician as these problems may indicate more serious complications or reactions. Prolonged use of this med can also result in serious side effects, but if used as instructed this should not be a concern for most patients.