Common side effects of generic Vibramycin medication include stomach upset, diarrhea, nausea, and headache; however, such side effects are usually temporary. Less common, but more serious, side effects can include jaundice (a yellowing of the eyes or skin), problems with vision and mental disturbances such as confusion and unusual thoughts. Patients suffering from any of these more serious side effects should immediately report this to their local physician. All tetracycline-based drugs also heighten the skin's sensitivity to sunlight, resulting in exaggerated sunburn, so persons taking this drug should avoid prolonged exposure to direct sunlight.