There are some side effects that occur with usage of Zyvox that may be serious and should be reported to a local physician. These effects include bruising, bleeding, pale skin, fevers, body aches, vision impairment, numbness, seizures, a burning sensation, watery or bloody diarrhea, tingling in the extremities, or signs of lactic acidosis. Other adverse reactions that are not serious include the following side effects: headaches, constipation, insomnia, itching, rashes, abnormal taste in the mouth, thrush, stomach pain, and vaginal discharge or itching.